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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IGFBP7 Polyclonal Antibody

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货号 TMAB-07557

Anti-IGFBP7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IGFBP7。Anti-IGFBP7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-IGFBP7 Polyclonal Antibody

Anti-IGFBP7 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07557

Anti-IGFBP7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IGFBP7。Anti-IGFBP7 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-IGFBP7 Polyclonal Antibody is a Rabbit antibody targeting IGFBP7. Anti-IGFBP7 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Cow,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景IGF-BPs form high affinity complexes with both IGF-I and IGF-II and act to control of the distribution, function and activity of IGFs in various cell tissues and body fluids. There are seven named IGF-BPs. IGFBP7 plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGFBP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. IGFBP7 is expressed in a wide range of normal human tissues and it usually shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGFBP7
抗原种属
Human
基因名称
IGFBP7
基因ID
3490
蛋白名称
Insulin-like growth factor-binding protein 7
Uniprot ID
Q16270
功能
Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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