Neurotrophin 3 Protein, Human, Recombinant

NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.

规格	价格/CNY		数量
20 μg	￥ 1,750	现货
100 μg	￥ 3,930	5日内发货
200 μg	￥ 6,720	5日内发货
500 μg	￥ 13,590	5日内发货

规格

价格/CNY

货期

数量

20 μg

￥ 1,750

现货

100 μg

￥ 3,930

5日内发货

200 μg

￥ 6,720

5日内发货

500 μg

￥ 13,590

5日内发货

生物活性

Measured by its binding ability in a functional ELISA. Immobilized human NT3 at 2 μg/ml (100 μl/well) can bind human TrkB-Fch . The EC50 of human TrkB-Fch is 120-350 ng/mL.

TargetMol Bioactive

产品描述

种属	Human
表达系统	E. coli
标签	Tag Free
蛋白编号	P20783-1
别名	NGF2, HDNF, NT-3, neurotrophin 3, NGF-2, NT3
蛋白构建	A DNA sequence encoding the human NT3 (P20783-1) (Tyr139-Thr257) was expressed and purified.
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	Approxiamtely 13.8 kDa

内毒素	Please contact us for more information.
缓冲液	Lyophilized from sterile PBS, pH 5. 2. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
复溶方法	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
存储	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
运输方式	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
研究背景	NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. NTF3 is capable of activating TrkB to induce anoikis resistance, and show that NTF3 is also a direct target of miR-200c. NTF3 is broadly expressed in the ovary, spleen, and other tissues. Diseases associated with NTF3 include Hypochondriasis and Demyelinating Disease.

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复溶计算器

重组蛋白稀释计算器

比活力计算器

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

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Neurotrophin 3 Protein, Human, Recombinant

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