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PAI-1 Protein, Human, Recombinant (His) V2

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产品编号 TMPY-01474U

PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.

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产品编号 TMPY-01474U

PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.

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生物活性	Measured by its ability to inhibit uPA cleavage of a peptide substrate, N-carbobenzyloxy-Gly-Gly-Arg-7-amido-4-methylcoumarin (Z-GGR-AMC). The IC50 value is < 35 nM. (QC Test)
产品描述	PAI-1 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P05121-1.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P05121-1
蛋白构建	Val24-Pro402
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	43.86 kDa (Predicted); 45-55 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Solution
缓冲液	Supplied as 0.22 μm filtered solution in 50 mM NaAC, 0.1M NaCl, 100mM L-arginine (pH 5.5).
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	PAI-1 (plasminogen activator inhibitor-1) is a member of plasminogen cascade with an inhibitory role in plasmin activation. PAI-1 is an important regulator of the fibrinolytic process and levels of this antifibrinolytic protein are elevated in diabetes and insulin resistant states.