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顶部生物活性储存和溶解信息计算器

Anti-VE-Cadherin Antibody-PE (2K899)

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产品编号 TMAY-00822P

别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody-PE (2K899) 是一种 PE-conjugated Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody-PE (2K899) 可用于 FCM。

Anti-VE-Cadherin Antibody-PE (2K899)

Anti-VE-Cadherin Antibody-PE (2K899)

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Rating icon 还可以
产品编号 TMAY-00822P 别名 cadherin 5, type 2 (vascular endothelium)

Anti-VE-Cadherin Antibody-PE (2K899) 是一种 PE-conjugated Mouse 抗体，靶向 VE-Cadherin。Anti-VE-Cadherin Antibody-PE (2K899) 可用于 FCM。

规格价格库存数量
25 T
¥ 895
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100 T
¥ 2,180
5日内发货
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产品介绍

生物活性
产品描述
Anti-VE-Cadherin Antibody-PE (2K899) is a PE-conjugated Mouse antibody targeting VE-Cadherin. Anti-VE-Cadherin Antibody-PE (2K899) can be used in FCM.
别名cadherin 5, type 2 (vascular endothelium)
Ig Type
Mouse IgG1
克隆号
2K899
交叉反应
Human
特异性
Human VE-Cadherin
验证活性
Flow cytometric analysis of Human CD144 expression on HUVEC cells. Cells were stained with PE-conjugated anti-Human CD144. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VE-Cadherin / CD144 / CDH5 (rh VE-Cadherin / CD144 / CDH5; CAA56306.1; Met1-Gln593) and conjugated with PE under optimum conditions, the unreacted PE was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Cadherins (Calcium dependent adhesion molecules) are a class of transmembrane proteins. Cadherin-5, also known as VE-cadherin, CDH5 and CD144, an endothelial specific cell-cell adhesion molecule, plays a pivotal role in the formation, maturation and remodeling of the vascular wall. VE-Cadherin is widely considered to be specific for vascular endothelia in which it is either the sole or the predominant cadherin, often co-existing with N-cadherin. This specificity of VE-cadherin for vascular endothelial cells is important not only in blood and lymph vessel biology and medicine, but also for cell-type-based diagnoses, notably those of metastatic tumors. As a classical cadherin, VE-Cadherin links endothelial cells together by homophilic interactions mediated by its extracellular part and associates intracellularly with the actin cytoskeleton via catenins. Mechanisms that regulate VE-cadherin-mediated adhesion are important for the control of vascular permeability and leukocyte extravasation. In addition to its adhesive functions, VE-Cadherin regulates various cellular processes such as cell proliferation and apoptosis and modulates vascular endothelial growth factor receptor functions. Consequently, VE-cadherin is essential during embryonic angiogenesis.
偶联与修饰
偶联
PE
其他可选修饰符
Unconjugated/APC/FITC
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human VE-Cadherin / CD144 / CDH5 Protein
抗原种属
Human
研究领域
Hemangioblast Markers, Cardiac Stem Cell Markers
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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关键词

vascular endotheliumcadherin 5, type 2

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