VU0364770 hydrochloride

Name: VU0364770 hydrochloride
Brand: TargetMol
SKU: T13317
Rating: 4.5 (1 reviews)

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产品编号 T13317Cas号 1414842-70-8

VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively).

VU0364770 hydrochloride

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产品编号 T13317Cas号 1414842-70-8

VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively).

规格	价格	库存
2 mg	¥ 295	5日内发货
5 mg	¥ 497	5日内发货
10 mg	¥ 747	5日内发货
1 mL x 10 mM (in DMSO)	¥ 983	5日内发货

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产品介绍

生物活性

产品描述	VU0364770 hydrochloride is a potent and selective mGlu4 positive allosteric modulator (PAM) (EC50s: 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively).
靶点活性	mGlu6:6.8 μM (EC50), mGlu4 (rat):290 nM (EC50), mGlu5:17.9 μM (EC50), mGlu4 (human):1.1 μM (EC50)

化学信息

分子量	269.13
分子式	C₁₂H₁₀Cl₂N₂O
CAS No.	1414842-70-8
密度	no data available

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 100 mg/mL (371.57 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7157 mL	18.5784 mL	37.1568 mL	185.7838 mL
5 mM	0.7431 mL	3.7157 mL	7.4314 mL	37.1568 mL
10 mM	0.3716 mL	1.8578 mL	3.7157 mL	18.5784 mL
20 mM	0.1858 mL	0.9289 mL	1.8578 mL	9.2892 mL
50 mM	0.0743 mL	0.3716 mL	0.7431 mL	3.7157 mL
100 mM	0.0372 mL	0.1858 mL	0.3716 mL	1.8578 mL