Name: 9A1P9
Brand: TargetMol
SKU: T84640
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,620

8-10周

5 mg (20.34 mM * 500 μL in Ethanol)

¥ 3,920

现货

生物活性

产品描述	9A1P9 is a multi-tailed ionizable cationic lipid featuring multiple hydrophobic chains and a protonatable headgroup. Under acidic conditions, 9A1P9 enhances electrostatic interactions with nucleic acids, promotes endosomal escape, and improves intracellular mRNA delivery efficiency. 9A1P9 is commonly used in the construction of lipid nanoparticle (LNP) systems and in delivery mechanism studies.
体外活性	与中性 pH 相比，9A1P9 在酸性内体腔室表现出更高的膜破坏活性[2]。
体内活性	9A1P9在小鼠体内可高效递送mRNA，其制备的iPLNP体系中9A1P9与Fluc mRNA的摩尔比为11,622:1，9A1P9与RNA的质量比为18:1 [2]。
别名	9A1P9

化学信息

分子量	491.73
分子式	C₂₇H₅₈NO₄P
CAS No.	2760467-57-8
Smiles	O=P(O)(OCCN(CCCCCCCC)CCCCCCCC)OCCCCCCCCC

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

9A1P9