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顶部生物活性储存和溶解信息计算器

Anti-CCNB1 Antibody (5T567)

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Anti-CCNB1 Antibody (5T567)
产品编号 TMAC-01033
别名 G2/mitotic-specific cyclin-B1, CCNB1, CCNB

Anti-CCNB1 Antibody (5T567) 是一种 Rabbit 抗体，靶向 CCNB1。Anti-CCNB1 Antibody (5T567) 可用于 WB,ICC/IF,IHC,IP。

Anti-CCNB1 Antibody (5T567)

Anti-CCNB1 Antibody (5T567)

Rating icon 还可以
Anti-CCNB1 Antibody (5T567)
产品编号 TMAC-01033 别名 G2/mitotic-specific cyclin-B1, CCNB1, CCNB

Anti-CCNB1 Antibody (5T567) 是一种 Rabbit 抗体，靶向 CCNB1。Anti-CCNB1 Antibody (5T567) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-CCNB1 Antibody (5T567) is a Rabbit antibody targeting CCNB1. Anti-CCNB1 Antibody (5T567) can be used in WB,ICC/IF,IHC,IP.
别名G2/mitotic-specific cyclin-B1, CCNB1, CCNB
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Cyclin B1 on different lysates using anti-Cyclin B1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: Daudi, Lane 3: K562.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cyclin B1 antibody. Counter stained with hematoxylin.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc 1). The Cdc/cyclin enzyme is subject to multiple levels of control, of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B enzyme; tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex. Evidence has established that B type cyclins not only act on M-phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The specificity of this effect is shown by the inability of either cyclin A or cyclin D1 to display any such stimulation of Cdc25A or Cdc25B.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P14635
化学信息
分子量Theoretical: 55 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

CCNB 1

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