Name: NVP-CGM097 sulfate
Brand: TargetMol
SKU: T12273
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

25 mg

¥ 8,930

1-2周

50 mg

¥ 11,600

1-2周

100 mg

¥ 17,500

1-2周

生物活性

产品描述	NVP-CGM097 sulfate is a potent and selective inhibitor of MDM2 (hMDM2, IC50 of 1.7±0.1 nM).
靶点活性	MDM2 (human):1.7±0.1 nM
体外活性	NVP-CGM097 is able to significantly redistribute wild-type p53 into the cell nucleus with an IC50 of 0.224 μM, demonstrating its ability to inhibit the p53:MDM2 interaction in living cells.?NVP-CGM097 significantly inhibits the proliferation of cells expressing wild-type p53, while sparing the p53 null cells with a 35-58-fold difference.?NVP-CGM097 inhibtis HCT116 (p53WT/WT) with IC50 of 454±136 nM[1].
别名	CGM097 sulfate

化学信息

分子量	757.34
分子式	C₃₈H₄₉ClN₄O₈S
CAS No.	1313367-56-4
Smiles	OS(O)(=O)=O.COc1cc2CC(=O)N([C@@H](c3ccc(Cl)cc3)c2cc1OC(C)C)c1ccc(cc1)N(C)C[C@H]1CC[C@@H](CC1)N1CCN(C)C(=O)C1
密度	no data available

储存&溶解度

存储

溶解度信息

H2O: 140 mg/mL (184.86 mM), Sonication is recommended.

溶液配制表

H2O

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

NVP-CGM097 sulfate