Name: Odesivimab
Brand: TargetMol
SKU: T77105
Price: 9360 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,980

现货

5 mg

¥ 4,680

现货

10 mg

¥ 6,310

现货

25 mg

¥ 9,360

现货

50 mg

待询

现货

生物活性

产品描述	Odesivimab (REGN-3471) is a humanized monoclonal antibody that specifically targets the Ebola virus glycoprotein (GP). Odesivimab binds to the FcγRIIIa receptor on the surface of immune effector cells via its Fc region, inducing antibody-dependent cellular immunity (ADCI) to eliminate infected cells or viral particles, thereby exerting an antiviral effect. Odesivimab has a Kd value of 7.74 nM for the extracellular domain of the Ebola virus glycoprotein from the recombinant Makona strain.
体外活性	Odesivimab 和 Atoltivimab 、 Maftivimab可联合配置成 REGN-EB3 ，IC50 值为 0.39 nM，可用于埃博拉病毒研究。 Odesivimab 与可溶性病毒糖蛋白表现出特异性结合。[1]
体内活性	Odesivimab 与 Atoltivimab 和 Maftivimab （REGN-3471，50 mg/kg）对埃博拉病毒感染的恒河猴模型具有保护作用。[1]
别名	奥西韦单抗, REGN-3471, REGN3471
反应种属	Virus
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Human IgG1 kappa
推荐同型对照	Human IgG1 kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量	146.16 kDa
CAS No.	2135632-30-1

储存&溶解度

存储	Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Odesivimab