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Anti-AMIGO1 Polyclonal Antibody

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货号 TMAB-02518

Anti-AMIGO1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AMIGO1。Anti-AMIGO1 Polyclonal Antibody 可用于 WB。

Anti-AMIGO1 Polyclonal Antibody

Anti-AMIGO1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02518

Anti-AMIGO1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AMIGO1。Anti-AMIGO1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-AMIGO1 Polyclonal Antibody is a Rabbit antibody targeting AMIGO1. Anti-AMIGO1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Cell projection; axon. Note: Associated with axons of neuronal cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AMIGO1
抗原种属
Human
基因名称
AMIGO1
基因ID
蛋白名称
Amphoterin-induced protein 1
Uniprot ID
功能
AMIGO1 promotes growth and fasciculation of neurites from cultured hippocampal neurons. It may be involved in fasciculation as well as myelination of developing neural axons and have a role in regeneration as well as neural plasticity in the adult nervous system. AMIGO1 may also mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.
化学信息
分子量Theoretical: 52 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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