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顶部生物活性储存和溶解信息计算器

Anti-Androgen receptor Antibody (3T582)

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Anti-Androgen receptor Antibody (3T582)
产品编号 TMAC-00200
别名 Nuclear receptor subfamily 3 group C member 4, NR3C4, Dihydrotestosterone receptor, DHTR, AR, Androgen receptor

Anti-Androgen receptor Antibody (3T582) 是一种 Rabbit 抗体，靶向 Androgen receptor。Anti-Androgen receptor Antibody (3T582) 可用于 WB,ICC/IF,IHC,FCM。

Anti-Androgen receptor Antibody (3T582)

Anti-Androgen receptor Antibody (3T582)

Rating icon 还可以
Anti-Androgen receptor Antibody (3T582)
产品编号 TMAC-00200 别名 Nuclear receptor subfamily 3 group C member 4, NR3C4, Dihydrotestosterone receptor, DHTR, AR, Androgen receptor

Anti-Androgen receptor Antibody (3T582) 是一种 Rabbit 抗体，靶向 Androgen receptor。Anti-Androgen receptor Antibody (3T582) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Androgen receptor Antibody (3T582) is a Rabbit antibody targeting Androgen receptor. Anti-Androgen receptor Antibody (3T582) can be used in WB,ICC/IF,IHC,FCM.
别名Nuclear receptor subfamily 3 group C member 4, NR3C4, Dihydrotestosterone receptor, DHTR, AR, Androgen receptor
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Androgen receptor antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Androgen receptor antibody. Counter stained with hematoxylin.
3. ICC staining Androgen receptor in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Androgen receptor in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining Androgen receptor in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. Flow cytometric analysis of MCF-7 cells with Androgen receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
IHC
FCM
推荐剂量
WB: 1:500-1000; IHC: 1:50-100; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and male reproductive physiology. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind the two biologically active androgens, testosterone (T) and dihydrotestosterone (DHT), with high and nearly identical affinities; however, the rates of association and dissociation of T are about three times more rapid than those of DHT. This difference has resulted in speculation as to whether these differences in binding kinetics could account for the different physiological effects of T and DHT. A striking feature of AR is its rapid degradation in the absence of ligand. It is now well established that androgen binding results in an at least six-fold increase in androgen stability and that ligand-induced stabilization of AR is highly androgen- specific.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P10275
化学信息
分子量Theoretical: 99 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

NR3C 4

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