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Anti-EFHD2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EFHD2。Anti-EFHD2 Polyclonal Antibody 可用于 WB。
Anti-EFHD2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EFHD2。Anti-EFHD2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-EFHD2 Polyclonal Antibody is a Rabbit antibody targeting EFHD2. Anti-EFHD2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Pig,Cow,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane raft. In immature B-cell line WEHI231. |
| 组织特异性 | Found in lymphocytes; preferentially expressed in CD8+ cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | EFHD2 is a 240 amino acid protein that regulates spontaneous apoptosis through the regulation of Bcl-xS abundance. Localized to membrane raft, Swiprosin-1 is expressed in lymphocytes and contains two EF-hand domains. The gene encoding Swiprosin-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| 免疫原 | KLH conjugated synthetic peptide: human EFHD2 |
| 抗原种属 | Human |
| 基因名称 | EFHD2 |
| 基因ID | |
| 蛋白名称 | EF-hand domain-containing protein D2 |
| Uniprot ID | |
| 功能 | May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
| 分子量 | Theoretical: 27 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |