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Anti-TGF beta 1 Antibody-HRP (6O746)

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Anti-TGF beta 1 Antibody-HRP (6O746)
产品编号 TMAY-01178H
别名 转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1

Anti-TGF beta 1 Antibody-HRP (6O746) 是一种 HRP-conjugated Rabbit 抗体,靶向 TGF beta 1。Anti-TGF beta 1 Antibody-HRP (6O746) 可用于 ELISA。

Anti-TGF beta 1 Antibody-HRP (6O746)

Anti-TGF beta 1 Antibody-HRP (6O746)

Rating icon 还可以
Anti-TGF beta 1 Antibody-HRP (6O746)
产品编号 TMAY-01178H 别名 转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1

Anti-TGF beta 1 Antibody-HRP (6O746) 是一种 HRP-conjugated Rabbit 抗体,靶向 TGF beta 1。Anti-TGF beta 1 Antibody-HRP (6O746) 可用于 ELISA。

规格价格库存数量
100 μg
¥ 3,485
5日内发货
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产品介绍

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产品描述
Anti-TGF beta 1 Antibody-HRP (6O746) is a HRP-conjugated Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Antibody-HRP (6O746) can be used in ELISA.
别名转化生长因子, transforming growth factor, β1, transforming growth factor, beta 1, TGF β1
Ig Type
Rabbit IgG
克隆号
6O746
交叉反应
Human
应用
推荐剂量
ELISA: 0.1-1 μg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human TGF-beta 1 (rh TGF-beta 1; TMPY-01133; NP_000651.3; Met 1-Ser 390), and conjugated with horseradish-peroxidase (HRP).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
HRP
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Human TGF-beta1 protein (TMPY-01133)
抗原种属
Human
研究领域
Early Mesodermal Lineage Markers, Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
运输方式Shipping with blue ice.

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