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Anti-Nucleoside phosphorylase/PNP Antibody (7S883) 是一种 Rabbit 抗体,靶向 Nucleoside phosphorylase/PNP。Anti-Nucleoside phosphorylase/PNP Antibody (7S883) 可用于 IHC-P。
Anti-Nucleoside phosphorylase/PNP Antibody (7S883) 是一种 Rabbit 抗体,靶向 Nucleoside phosphorylase/PNP。Anti-Nucleoside phosphorylase/PNP Antibody (7S883) 可用于 IHC-P。
产品描述 | Anti-Nucleoside phosphorylase/PNP Antibody (7S883) is a Rabbit antibody targeting Nucleoside phosphorylase/PNP. Anti-Nucleoside phosphorylase/PNP Antibody (7S883) can be used in IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7S883 |
交叉反应 | Human |
验证活性 | 1. Immunochemical staining of human PNP in human placenta with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human PNP in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
应用 | IHC-P |
推荐剂量 | IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human PNP (rh PNP; TMPY-02279; P00491; Met1-Ser289). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immunodeficiency. Purine nucleoside phosphorylase (PNP) is a target for leukemia, gout, and autoimmune disorders. |
偶联 | Unconjugated |
免疫原 | Recombinant Human PNP protein (TMPY-02279) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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