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Anti-ADIPOR1 Antibody (2S638)

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Anti-ADIPOR1 Antibody (2S638)
产品编号 TMAC-00093
别名 TESBP1A, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member 1, PAQR1, ADIPOR1, Adiponectin receptor protein 1

Anti-ADIPOR1 Antibody (2S638) 是一种 Rabbit 抗体,靶向 ADIPOR1。Anti-ADIPOR1 Antibody (2S638) 可用于 WB,ICC/IF,IHC,FCM。

Anti-ADIPOR1 Antibody (2S638)

Anti-ADIPOR1 Antibody (2S638)

Rating icon 还可以
Anti-ADIPOR1 Antibody (2S638)
产品编号 TMAC-00093 别名 TESBP1A, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member 1, PAQR1, ADIPOR1, Adiponectin receptor protein 1

Anti-ADIPOR1 Antibody (2S638) 是一种 Rabbit 抗体,靶向 ADIPOR1。Anti-ADIPOR1 Antibody (2S638) 可用于 WB,ICC/IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADIPOR1 Antibody (2S638) is a Rabbit antibody targeting ADIPOR1. Anti-ADIPOR1 Antibody (2S638) can be used in WB,ICC/IF,IHC,FCM.
别名TESBP1A, Progestin and adipoQ receptor family member I, Progestin and adipoQ receptor family member 1, PAQR1, ADIPOR1, Adiponectin receptor protein 1
Ig Type
IgG
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of ADIPOR1 on human skeletal muscle lysates using anti-ADIPOR1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-ADIPOR1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-ADIPOR1 antibody. Counter stained with hematoxylin.
4. ICC staining ADIPOR1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining ADIPOR1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining ADIPOR1 in LO2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. Flow cytometric analysis of HepG2 cells with ADIPOR1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Adiponectin is a circulating hormone secreted by adipocytes that improves the metabolism of glucose and lipids, and is expressed at low levels in those with obesity and diabetes. Adiponectin receptors AdipoR1 and AdipoR2, also designated progestin and adipoQ receptor family members I and II, respectively, regulate fatty acid oxidation and the uptake of glucose by adiponectin. Each receptor activates a unique set of signaling molecules including AMPK, p38 MAPK and PPARα. AdipoR1 has a high-affinity for globular adiponectin and low-affinity for full-length adiponectin, while AdipoR2 has an intermediate affinity for both forms. AdipoR1 and AdipoR2 are mainly expressed in liver and muscle. Adiponectin, AdipoR1 and AdipoR2 are all associated with body composition, Insulin sensitivity, and metabolic parameters. Physical training increases circulating adiponectin and mRNA expression of AdipoR1 and AdipoR2 in muscle, which may mediate the improvement of Insulin resistance and the metabolic syndrome in response to exercise.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 43 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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