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IL-7 Protein, Human, Recombinant V2

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产品编号 TMPY-03383U

IL-7 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P13232.

IL-7 Protein, Human, Recombinant V2

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产品编号 TMPY-03383U

IL-7 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P13232.

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产品信息

生物活性	Immobilized Human IL-7 at 0.5 μg/ml (100 μl/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 52.5 ng/ml determined by ELISA. Human IL-7 R alpha, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-7, No Tag with an affinity constant of 4.18 nM as determined in SPR assay (Biacore T200). Measured in a cell proliferation assay using murine 2E8 cells. The ED50 for this effect is 0.1 - 0.5 ng/mL (QC tested).
产品描述	IL-7 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P13232.
种属	Human
表达系统	E. coli
蛋白编号	P13232
别名	白细胞介素,Interleukin-7,interleukin 7,IL-7
蛋白构建	Asp26-His177
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	17.5 kDa (Predicted and reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in 25mM PB, 250 mM NaCl (pH 6.8). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor.