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顶部生物活性储存和溶解信息计算器

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

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产品编号 T37634Cas号 1233715-33-7

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

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Rating icon 还可以
产品编号 T37634Cas号 1233715-33-7

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

规格价格库存数量
100 μg
¥ 2,870
35日内发货
250 μg
¥ 6,880
35日内发货
500 μg
¥ 12,800
35日内发货
1 mg
¥ 23,000
35日内发货
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17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid 相关产品

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生物活性
产品描述
Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).
化学信息
分子量344.495
分子式C22H32O3
CAS No.1233715-33-7
密度no data available
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 10 mg/mL (29.03 mM), Sonication is recommended.
Ethanol: 20 mg/mL (58.06 mM), Sonication is recommended.
DMF: 15 mg/mL (43.54 mM), Sonication is recommended.
溶液配制表
DMSO/DMF/Ethanol
1mg5mg10mg50mg
1 mM2.9028 mL14.5140 mL29.0280 mL145.1400 mL
5 mM0.5806 mL2.9028 mL5.8056 mL29.0280 mL
10 mM0.2903 mL1.4514 mL2.9028 mL14.5140 mL
20 mM0.1451 mL0.7257 mL1.4514 mL7.2570 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments 一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH2O， 那么您的工作液浓度为 2 mg/mL 。
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent （ 母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法: 取 50μLDMSOTargetMol | reagent 母液，添加 300 μLPEG300TargetMol | reagent 混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300/ PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

17-oxo-7,10,13,15,19Docosapentaenoic Acid17 oxo 7(Z),10(Z),13(Z),15(E),19(Z) Docosapentaenoic Acid17oxo7(Z),10(Z),13(Z),15(E),19(Z)Docosapentaenoic Acid

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