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Anti-PRSS3 Antibody (6K687)

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产品编号 TMAY-02124

Anti-PRSS3 Antibody (6K687) 是一种 Rabbit 抗体,靶向 PRSS3。Anti-PRSS3 Antibody (6K687) 可用于 ELISA。

Anti-PRSS3 Antibody (6K687)

Anti-PRSS3 Antibody (6K687)

Rating icon 还可以
产品编号 TMAY-02124

Anti-PRSS3 Antibody (6K687) 是一种 Rabbit 抗体,靶向 PRSS3。Anti-PRSS3 Antibody (6K687) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-PRSS3 Antibody (6K687) is a Rabbit antibody targeting PRSS3. Anti-PRSS3 Antibody (6K687) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6K687
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Trypsin-3 / PRSS3 (rh Trypsin-3 / PRSS3; TMPY-01897; P35030-3; Met1-Ser247).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3 / PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Trypsin-3 / PRSS3 protein (TMPY-01897)
抗原种属
Human
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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