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Anti-PRSS3 Antibody (6K687) 是一种 Rabbit 抗体,靶向 PRSS3。Anti-PRSS3 Antibody (6K687) 可用于 ELISA。
Anti-PRSS3 Antibody (6K687) 是一种 Rabbit 抗体,靶向 PRSS3。Anti-PRSS3 Antibody (6K687) 可用于 ELISA。
产品描述 | Anti-PRSS3 Antibody (6K687) is a Rabbit antibody targeting PRSS3. Anti-PRSS3 Antibody (6K687) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6K687 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Trypsin-3 / PRSS3 (rh Trypsin-3 / PRSS3; TMPY-01897; P35030-3; Met1-Ser247). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their inhibitors seems to be important for the development of CP. The trypsin inhibitor-degrading activity qualified PRSS3 as a candidate for a novel CP susceptibility gene. Trypsin-3 / PRSS3 has been implicated as a putative tumor suppressor gene due to its loss of expression, which is correlated with promoter hypermethylation, in esophageal squamous cell carcinoma and gastric adenocarcinoma. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Trypsin-3 / PRSS3 protein (TMPY-01897) |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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