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Anti-Beta-casein Polyclonal Antibody
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产品编号 TMAB-00227
Anti-Beta-casein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Beta-casein。Anti-Beta-casein Polyclonal Antibody 可用于 WB。
Anti-Beta-casein Polyclonal Antibody
Anti-Beta-casein Polyclonal Antibody
还可以产品编号 TMAB-00227
Anti-Beta-casein Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Beta-casein。Anti-Beta-casein Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-Beta-casein Polyclonal Antibody is a Rabbit antibody targeting Beta-casein. Anti-Beta-casein Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Cow,Sheep,Goat |
| 验证活性 | Sample: Lane 1: Milk (Goat) Lysate at 2 μg Lane 2: Milk (Cow) Lysate at 30 μg Lane 3: Milk (Cow) Lysate at 3 μg Lane 4: Milk (Human) Lysate at 30 μg Primary: Anti-Beta-casein (TMAB-00227) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kDa Observed band size: 25-29 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Milk proteins are crucial for the development of all newborn mammals and caseins constitute the major proteins in mammalian milk. b- and k-caseins are the only caseins present in human milk. The b-casein/k-casein ratio is higher in colostrum than in transitional and mature milk and is related to a better digestibility of colostrum casein micelles by the neonate during the first days of life. Human b-casein-encoding gene (Bca) contains a highly phosphorylated site, which is responsible for the calcium-binding capacity of b-casein. A common set of transcription factors are required for the expression of b-casein. Multiple binding sites for Stat5, C/EBPb (CCAAT/enchancer-binding protein) and several half-sites for glucocorticoid receptor (GR) are identified in the distal human enhancer of the b-casein gene. b-casein gene transcription is regulated primarily by a composite response element (CoRE), which integrates signaling from the lactogenic hormones PRL, insulin and hydrocortisone in mammary epithelial cells. NFkB functions as a negative regulator of b-casein gene expression during pregnancy by interfering with Stat5 tyrosine phosphorylation |
| 免疫原 | KLH conjugated synthetic peptide: sheep Beta-casein |
| 抗原种属 | Sheep |
| 基因ID | |
| 研究领域 | Pol II Transcription,Transcription Factors,Coat Proteins |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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