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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Fibrinogen alpha chain Polyclonal Antibody

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货号 TMAB-06021

Anti-Fibrinogen alpha chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fibrinogen alpha chain。Anti-Fibrinogen alpha chain Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Fibrinogen alpha chain Polyclonal Antibody

Anti-Fibrinogen alpha chain Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06021

Anti-Fibrinogen alpha chain Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fibrinogen alpha chain。Anti-Fibrinogen alpha chain Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-Fibrinogen alpha chain Polyclonal Antibody is a Rabbit antibody targeting Fibrinogen alpha chain. Anti-Fibrinogen alpha chain Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Plasma.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Fibrinogen alpha chain
抗原种属
Human
基因名称
FGA/FGB/FGG
基因ID
2243
蛋白名称
Fibrinogen alpha chain
Uniprot ID
P02671
功能
Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
化学信息
分子量Theoretical: 91 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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