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Anti-FOXG1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOXG1。Anti-FOXG1 Polyclonal Antibody 可用于 WB。
Anti-FOXG1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOXG1。Anti-FOXG1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-FOXG1 Polyclonal Antibody is a Rabbit antibody targeting FOXG1. Anti-FOXG1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Chicken,Dog,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expression is restricted to the neurons of the developing telencephalon. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The winged-helix transcriptional repressor (WH) BF-1 gene encodes brain factor 1 (BF-1), also known as foxg1, and is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (1–4). WH proteins are a family of putative transcriptional regulators with diverse roles in development, and are characterized by a highly conserved DNA binding structure, the WH domain (1,5,6). BF-1 plays a critical role in the development of the cerebral hemispheres of the brain and targeted disruption of the gene leads to severe defects in the development of telencephalic structures, such as the cerebral cortex and basal ganglia (1). The loss of BF-1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (1,7). BF-1 is expressed by E8.5 in telencephalic progenitors (1). It may also regulate the response of cerebral cortical progenitors to environmental cues (1). |
| 免疫原 | KLH conjugated synthetic peptide: human FOXG1 |
| 抗原种属 | Human |
| 基因名称 | FOXG1 |
| 基因ID | |
| 蛋白名称 | Forkhead box protein G1 |
| Uniprot ID | |
| 功能 | Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon. |
| 分子量 | Theoretical: 52 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |