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Anti-GATA3 Antibody (3N332)

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货号 TMAB-06355

Anti-GATA3 Antibody (3N332) 是一种 Rabbit 抗体，靶向 GATA3。Anti-GATA3 Antibody (3N332) 可用于 IHC-P,IHC-Fr,WB。

Anti-GATA3 Antibody (3N332)

Anti-GATA3 Antibody (3N332)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06355

Anti-GATA3 Antibody (3N332) 是一种 Rabbit 抗体，靶向 GATA3。Anti-GATA3 Antibody (3N332) 可用于 IHC-P,IHC-Fr,WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-GATA3 Antibody (3N332) is a Rabbit antibody targeting GATA3. Anti-GATA3 Antibody (3N332) can be used in IHC-P,IHC-Fr,WB.
Ig Type
IgG
克隆号
3N332
反应种属
Human,Mouse
应用IHC-PIHC-FrWB
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性T-cells and endothelial cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as in erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. Both GATA-4 and GATA-6 are found in heart, pancreas and ovary; lung and liver tissues exhibit GATA-6, but not GATA-4 expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart. Although expression patterns of the various GATA transcription factors may overlap, it is not yet apparent how the GATA factors are able to discriminate in binding their appropriate target sites.
抗原信息
免疫原
A synthesized peptide: human GATA3
基因名称
GATA3
基因ID
2625
蛋白名称
Trans-acting T-cell-specific transcription factor GATA-3
功能
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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