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顶部生物活性储存和溶解信息计算器

Anti-CD40 Antibody (7T589)

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产品编号 TMAY-01156

别名 TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936

Anti-CD40 Antibody (7T589) 是一种 Mouse 抗体，靶向 CD40。Anti-CD40 Antibody (7T589) 可用于 ELISA。

Anti-CD40 Antibody (7T589)

Anti-CD40 Antibody (7T589)

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Rating icon 还可以
产品编号 TMAY-01156 别名 TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936

Anti-CD40 Antibody (7T589) 是一种 Mouse 抗体，靶向 CD40。Anti-CD40 Antibody (7T589) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 780
5日内发货
100 μL
¥ 2,294
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD40 Antibody (7T589) is a Mouse antibody targeting CD40. Anti-CD40 Antibody (7T589) can be used in ELISA.
别名TRAP, Tnfrsf5, T-BAM, p50, IMD3, Igm, HIGM1, gp39, CD40 molecule, TNF receptor superfamily member 5, Bp50, AI326936
Ig Type
Mouse IgG2b
克隆号
7T589
交叉反应
Human
特异性
Human CD40/TNFRSF5
No cross-reactivity in ELISA with
Human CD27 / TNFRSF7
Mouse CD27 / TNFRSF7
Human CD30 / TNFRSF8
Human DR6 / TNFRSF21
Human CD137 / 4-1BB
Human TNFRSF1B / CD120b
Human HVEM / TNFRSF14
Mouse HVEM / TNFRSF14
Human RELT / TNFRSF19L
Human cell lysate (293 cell line)
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD40 extracellular domain (rh CD40; TMPY-01181; NP_001241.1; Met 1-Arg 193). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD40 protein (TMPY-01181)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

IMD-3IMD 3HIGM-1HIGM 1GP-39GP 39AI-326936AI 326936

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