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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MAGI1 Polyclonal Antibody

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货号 TMAB-08527

Anti-MAGI1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAGI1。Anti-MAGI1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MAGI1 Polyclonal Antibody

Anti-MAGI1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08527

Anti-MAGI1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MAGI1。Anti-MAGI1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAGI1 Polyclonal Antibody is a Rabbit antibody targeting MAGI1. Anti-MAGI1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction; cell membrane; tight junction; peripheral membrane protein. Localizes to epithelial cells tight junctions.
组织特异性Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAGI1
抗原种属
Human
基因名称
MAGI1
基因ID
9223
蛋白名称
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
Uniprot ID
Q96QZ7
功能
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).
化学信息
分子量Theoretical: 137 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
  • 配液 计算器
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