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Anti-CD3 epsilon/CD3e Polyclonal Antibody

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Anti-CD3 epsilon/CD3e Polyclonal Antibody
产品编号 TMAB-00351
别名 T3e, CD3epsilon, CD3

Anti-CD3 epsilon/CD3e Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Polyclonal Antibody 可用于 WB。

Anti-CD3 epsilon/CD3e Polyclonal Antibody

Anti-CD3 epsilon/CD3e Polyclonal Antibody

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Anti-CD3 epsilon/CD3e Polyclonal Antibody
产品编号 TMAB-00351 别名 T3e, CD3epsilon, CD3

Anti-CD3 epsilon/CD3e Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD3 epsilon/CD3e。Anti-CD3 epsilon/CD3e Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,975
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200 μL
¥ 2,795
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产品介绍

生物活性
产品描述
Anti-CD3 epsilon/CD3e Polyclonal Antibody is a Rabbit antibody targeting CD3 epsilon/CD3e. Anti-CD3 epsilon/CD3e Polyclonal Antibody can be used in WB.
别名T3e, CD3epsilon, CD3
Ig Type
IgG
交叉反应
Mouse (predicted:Pig)
验证活性
Sample:
Lane 1: Recombinant mouse CD3E protein, C-mFc (HEK293)
Primary: Anti-CD3 (TMAB-00351) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 36 kDa
应用
WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
抗原信息
免疫原
KLH conjugated synthetic peptide: pig CD3
抗原种属
Pig
基因名称
CD3E
蛋白名称
T-cell surface glycoprotein CD3 epsilon chain
研究领域
Regulatory T Cells,CD,cd3,Human Lineage Negative
功能
The CD3 complex mediates signal transduction.
化学信息
分子量Theoretical: 20 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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