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Anti-TFPI Polyclonal Antibody

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货号 TMAB-01825

别名 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI

Anti-TFPI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TFPI。Anti-TFPI Polyclonal Antibody 可用于 WB。

Anti-TFPI Polyclonal Antibody

Anti-TFPI Polyclonal Antibody

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货号 TMAB-01825 别名 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI

Anti-TFPI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TFPI。Anti-TFPI Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-TFPI Polyclonal Antibody is a Rabbit antibody targeting TFPI. Anti-TFPI Polyclonal Antibody can be used in WB.
别名tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit)
验证活性
Sample:
Heart (Mouse) Lysate at 40 μg
Lung (Rat) Lysate at 40 μg
Primary: Anti-TFPI (TMAB-01825) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 52 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform Alpha: Secreted. Isoform Beta: Microsome membrane; Lipid-anchor, GPI-anchor.
组织特异性Mostly in endothelial cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human TFPI
抗原种属
Human
基因名称
TFPI
基因ID
7035
蛋白名称
Tissue factor pathway inhibitor
Uniprot ID
P10646
研究领域
Platelets,Extrinsic
功能
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.
化学信息
分子量Theoretical: 32 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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关键词

tissue factor pathway inhibitorTFPI-1TFPI 1lipoprotein-associated coagulation inhibitor
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