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Anti-TFPI Polyclonal Antibody
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产品编号 TMAB-01825
别名 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI
Anti-TFPI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TFPI。Anti-TFPI Polyclonal Antibody 可用于 WB。
Anti-TFPI Polyclonal Antibody
Anti-TFPI Polyclonal Antibody
还可以产品编号 TMAB-01825 别名 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI
Anti-TFPI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TFPI。Anti-TFPI Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-TFPI Polyclonal Antibody is a Rabbit antibody targeting TFPI. Anti-TFPI Polyclonal Antibody can be used in WB. |
| 疾病造模方案 | |
| 别名 | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), TFPI1, TFI, LACI, EPI |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit) |
| 验证活性 | Sample: Heart (Mouse) Lysate at 40 μg Lung (Rat) Lysate at 40 μg Primary: Anti-TFPI (TMAB-01825) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kDa Observed band size: 52 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform Alpha: Secreted. Isoform Beta: Microsome membrane; Lipid-anchor, GPI-anchor. |
| 组织特异性 | Mostly in endothelial cells. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. |
| 免疫原 | KLH conjugated synthetic peptide: human TFPI |
| 抗原种属 | Human |
| 基因名称 | TFPI |
| 基因ID | |
| 蛋白名称 | Tissue factor pathway inhibitor |
| Uniprot ID | |
| 研究领域 | Platelets,Extrinsic |
| 功能 | Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. |
| 分子量 | Theoretical: 32 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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