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Anti-KHDRBS2 Antibody (3H737)

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Anti-KHDRBS2 Antibody (3H737)
产品编号 TMAC-02309
别名 SLM-1, SLM1, SLM 1, signal transduction-associated protein 2, signal transduction associated protein 2, signal transduction associated 2, Sam68-like mammalian protein 1, Sam68 like mammalian protein 1, RNA-binding, RNA binding, MGC26664, khdrbs 2, KHDR2_HUMAN, KH domain-containing, KH domain containing, hSLM-1, hSLM 1, FLJ38664, bA535F17.1, 6330586C16Rik

Anti-KHDRBS2 Antibody (3H737) 是一种 Mouse 抗体,靶向 KHDRBS2。Anti-KHDRBS2 Antibody (3H737) 可用于 WB,IHC,FCM。

Anti-KHDRBS2 Antibody (3H737)

Anti-KHDRBS2 Antibody (3H737)

Rating icon 还可以
Anti-KHDRBS2 Antibody (3H737)
产品编号 TMAC-02309 别名 SLM-1, SLM1, SLM 1, signal transduction-associated protein 2, signal transduction associated protein 2, signal transduction associated 2, Sam68-like mammalian protein 1, Sam68 like mammalian protein 1, RNA-binding, RNA binding, MGC26664, khdrbs 2, KHDR2_HUMAN, KH domain-containing, KH domain containing, hSLM-1, hSLM 1, FLJ38664, bA535F17.1, 6330586C16Rik

Anti-KHDRBS2 Antibody (3H737) 是一种 Mouse 抗体,靶向 KHDRBS2。Anti-KHDRBS2 Antibody (3H737) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,990
5日内发货
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产品介绍

生物活性
产品描述
Anti-KHDRBS2 Antibody (3H737) is a Mouse antibody targeting KHDRBS2. Anti-KHDRBS2 Antibody (3H737) can be used in WB,IHC,FCM.
别名SLM-1, SLM1, SLM 1, signal transduction-associated protein 2, signal transduction associated protein 2, signal transduction associated 2, Sam68-like mammalian protein 1, Sam68 like mammalian protein 1, RNA-binding, RNA binding, MGC26664, khdrbs 2, KHDR2_HUMAN, KH domain-containing, KH domain containing, hSLM-1, hSLM 1, FLJ38664, bA535F17.1, 6330586C16Rik
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of KHDRBS2 on human KHDRBS2 recombinant protein using anti-KHDRBS2 antibody at 1/1,000 dilution.
2. Western blot analysis of KHDRBS2 on different cell lysate using anti-KHDRBS2 antibody at 1/1,000 dilution. Positive control: Line1: K562, Line2: HEK293, Line3: NTERA-2, Line4: Hela, Line5: HepG2, Line6: Jurkat, Line7: A431, Line8: NIH/3T3.
3. Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin.
5. Flow cytometric analysis of K562 cells with KHDRBS2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 39 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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