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Anti-KHDRBS2 Antibody (3H737) 是一种 Mouse 抗体,靶向 KHDRBS2。Anti-KHDRBS2 Antibody (3H737) 可用于 WB,IHC,FCM。
Anti-KHDRBS2 Antibody (3H737) 是一种 Mouse 抗体,靶向 KHDRBS2。Anti-KHDRBS2 Antibody (3H737) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,995 | 5日内发货 | |
100 μL | ¥ 2,990 | 5日内发货 |
产品描述 | Anti-KHDRBS2 Antibody (3H737) is a Mouse antibody targeting KHDRBS2. Anti-KHDRBS2 Antibody (3H737) can be used in WB,IHC,FCM. |
别名 | SLM-1, SLM1, SLM 1, signal transduction-associated protein 2, signal transduction associated protein 2, signal transduction associated 2, Sam68-like mammalian protein 1, Sam68 like mammalian protein 1, RNA-binding, RNA binding, MGC26664, khdrbs 2, KHDR2_HUMAN, KH domain-containing, KH domain containing, hSLM-1, hSLM 1, FLJ38664, bA535F17.1, 6330586C16Rik |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of KHDRBS2 on human KHDRBS2 recombinant protein using anti-KHDRBS2 antibody at 1/1,000 dilution. 2. Western blot analysis of KHDRBS2 on different cell lysate using anti-KHDRBS2 antibody at 1/1,000 dilution. Positive control: Line1: K562, Line2: HEK293, Line3: NTERA-2, Line4: Hela, Line5: HepG2, Line6: Jurkat, Line7: A431, Line8: NIH/3T3. 3. Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of K562 cells with KHDRBS2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 39 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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