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Anti-FOXP3 Antibody (9K907)

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Anti-FOXP3 Antibody (9K907)
产品编号 TMAC-01561

Anti-FOXP3 Antibody (9K907) 是一种 Rabbit 抗体,靶向 FOXP3。Anti-FOXP3 Antibody (9K907) 可用于 WB,FCM,IHC。

Anti-FOXP3 Antibody (9K907)

Anti-FOXP3 Antibody (9K907)

Rating icon 还可以
Anti-FOXP3 Antibody (9K907)
产品编号 TMAC-01561

Anti-FOXP3 Antibody (9K907) 是一种 Rabbit 抗体,靶向 FOXP3。Anti-FOXP3 Antibody (9K907) 可用于 WB,FCM,IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-FOXP3 Antibody (9K907) is a Rabbit antibody targeting FOXP3. Anti-FOXP3 Antibody (9K907) can be used in WB,FCM,IHC.
Ig Type
IgG
交叉反应
Human
验证活性
1. Flow cytometric analysis of Raji cells with FOXP3 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
2. Immunohistochemical analysis of paraffin-embedded Human squamous carcinoma, using the Antibody at 1:100 dilution.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:10-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. The gene encoding human FOXP1 maps to chromosome 3p14.1, and the gene encoding human FOXP2 maps to chromosome 7q31. The gene encoding FOXP3, a third member of this family, maps to chromosome Xp11.23. Mutations in this gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein, also known as scurfin, is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 50 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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