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Anti-SLAM/CD150 Antibody-HRP (8O593) 是一种 HRP-conjugated Mouse 抗体,靶向 SLAM/CD150。Anti-SLAM/CD150 Antibody-HRP (8O593) 可用于 ELISA。
Anti-SLAM/CD150 Antibody-HRP (8O593) 是一种 HRP-conjugated Mouse 抗体,靶向 SLAM/CD150。Anti-SLAM/CD150 Antibody-HRP (8O593) 可用于 ELISA。
产品描述 | Anti-SLAM/CD150 Antibody-HRP (8O593) is a HRP-conjugated Mouse antibody targeting SLAM/CD150. Anti-SLAM/CD150 Antibody-HRP (8O593) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 8O593 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 0.1-1 μg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD150 / SLAM / SLAMF1 (rh CD150 / SLAM / SLAMF1; TMPY-01016; NP_003028.1; Met1-Pro258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of interferon γ (IFN-γ) in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus. |
偶联 | HRP |
其他可选修饰符 | Unconjugated |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human CD150 / SLAM / SLAMF1 Protein (TMPY-01016) |
抗原种属 | Human |
研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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