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Anti-RUVBL1 Antibody (1O231)
还可以产品编号 TMAY-02688
别名 TIP49A, TIP49, TIH1, RVB1, RuvB-like AAA ATPase 1, Pontin52, PONTIN, NMP238, INO80H, ECP54
Anti-RUVBL1 Antibody (1O231) 是一种 Mouse 抗体，靶向 RUVBL1。Anti-RUVBL1 Antibody (1O231) 可用于 IHC-P。
Anti-RUVBL1 Antibody (1O231)
Anti-RUVBL1 Antibody (1O231)
还可以产品编号 TMAY-02688 别名 TIP49A, TIP49, TIH1, RVB1, RuvB-like AAA ATPase 1, Pontin52, PONTIN, NMP238, INO80H, ECP54
Anti-RUVBL1 Antibody (1O231) 是一种 Mouse 抗体，靶向 RUVBL1。Anti-RUVBL1 Antibody (1O231) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-RUVBL1 Antibody (1O231) is a Mouse antibody targeting RUVBL1. Anti-RUVBL1 Antibody (1O231) can be used in IHC-P. |
| 别名 | TIP49A, TIP49, TIH1, RVB1, RuvB-like AAA ATPase 1, Pontin52, PONTIN, NMP238, INO80H, ECP54 |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 1O231 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human RUVBL1 in human colon carcinoma with mouse monoclonal antibody (1:100000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human RUVBL1 in human testis with mouse monoclonal antibody (1:100000, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:20000-1:100000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RUVBL1 / RVB1 (rh RUVBL1 / RVB1; TMPY-03263; Q9Y265-1; Met1-Lys456). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | RUVBL1, also known as RVB1, is a component of the NuA4 histone acetyltransferase complex and belongs to the RuvB family. RUVBL1 is ubiquitously expressed with high expression in heart, skeletal muscle and testis. It possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. RUVBL1 is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex. It also is essential for cell proliferation. RUVBL1 may be able to bind plasminogen at cell surface and enhance plasminogen activation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human RUVBL1 / RVB1 Protein (TMPY-03263) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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