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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ZZZ3 Polyclonal Antibody

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货号 TMAB-14470

Anti-ZZZ3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZZZ3。Anti-ZZZ3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ZZZ3 Polyclonal Antibody

Anti-ZZZ3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14470

Anti-ZZZ3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ZZZ3。Anti-ZZZ3 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-ZZZ3 Polyclonal Antibody is a Rabbit antibody targeting ZZZ3. Anti-ZZZ3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ZZZ3 (ZZ-type zinc finger-containing protein 3) is a 903 amino acid protein that contains one HTH myb-type DNA-binding domain and one ZZ-type zinc finger. Phosphorylated upon DNA damage by ATM or ATR, ZZZ3 is a subunit of the ATAC complex, which is composed of GCN5, CRP2BP, ADA3, TADA2L, DR1, CCDC101, YEATS2, WDR5 and MBIP. The ATAC complex has histone acetyltransferase activity on histones H3 and H4. ZZZ3 is expressed as four isoforms produced by alternative splicing and is encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ZZZ3
抗原种属
Human
基因名称
ZZZ3
基因ID
26009
蛋白名称
ZZ-type zinc finger-containing protein 3
Uniprot ID
Q8IYH5
功能
Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
化学信息
分子量Theoretical: 102 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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