- 全部删除
- 您的购物车当前为空
Anti-Phospho-PTK2 (Y397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Y397)。Anti-Phospho-PTK2 (Y397) Antibody (9L726) 可用于 WB,ICC/IF。
Anti-Phospho-PTK2 (Y397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Y397)。Anti-Phospho-PTK2 (Y397) Antibody (9L726) 可用于 WB,ICC/IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-Phospho-PTK2 (Tyr397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Tyr397)。Anti-Phospho-PTK2 (Tyr397) Antibody (9L726) 可用于 WB,ICC/IF。 |
别名 | PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. ICC staining phospho-FAK (Y397) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining phospho-FAK (Y397) in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining phospho-FAK (Y397) in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival, and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by Integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phosphorylation of FAK Tyr 397 decreases during serum starvation, contact inhibition, and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human FAK around the phosphorylation site of Tyr397 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 119 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
评论内容