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Anti-Phospho-PTK2 (Tyr397) Antibody (9L726)

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Anti-Phospho-PTK2 (Tyr397) Antibody (9L726)
产品编号 TMAC-03215
别名 PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)

Anti-Phospho-PTK2 (Y397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Y397)。Anti-Phospho-PTK2 (Y397) Antibody (9L726) 可用于 WB,ICC/IF。

Anti-Phospho-PTK2 (Tyr397) Antibody (9L726)

Anti-Phospho-PTK2 (Tyr397) Antibody (9L726)

Rating icon 还可以
Anti-Phospho-PTK2 (Tyr397) Antibody (9L726)
产品编号 TMAC-03215 别名 PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)

Anti-Phospho-PTK2 (Y397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Y397)。Anti-Phospho-PTK2 (Y397) Antibody (9L726) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PTK2 (Tyr397) Antibody (9L726) 是一种 Rabbit 抗体,靶向 Phospho-PTK2 (Tyr397)。Anti-Phospho-PTK2 (Tyr397) Antibody (9L726) 可用于 WB,ICC/IF。
别名PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. ICC staining phospho-FAK (Y397) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining phospho-FAK (Y397) in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining phospho-FAK (Y397) in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival, and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by Integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phosphorylation of FAK Tyr 397 decreases during serum starvation, contact inhibition, and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human FAK around the phosphorylation site of Tyr397
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 119 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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