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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PADI4 Polyclonal Antibody

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货号 TMAB-09920

Anti-PADI4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PADI4。Anti-PADI4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-PADI4 Polyclonal Antibody

Anti-PADI4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09920

Anti-PADI4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PADI4。Anti-PADI4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PADI4 Polyclonal Antibody is a Rabbit antibody targeting PADI4. Anti-PADI4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils and neutrophils.
组织特异性Expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PADI4 (peptidyl arginine deiminase, type IV) catalyzes the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PADI4
抗原种属
Human
基因名称
PADI4
基因ID
23569
蛋白名称
Protein-arginine deiminase type-4
Uniprot ID
Q9UM07
功能
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
化学信息
分子量Theoretical: 74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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