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顶部生物活性储存和溶解信息计算器

Anti-NRAS Antibody (8O77)

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Anti-NRAS Antibody (8O77)
产品编号 TMAC-03537
别名 NS6, NRAS1, N-ras, neuroblastoma RAS viral (v-ras) oncogene homolog, NCMS, CMNS, ALPS4

Anti-NRAS Antibody (8O77) 是一种 Rabbit 抗体，靶向 NRAS。Anti-NRAS Antibody (8O77) 可用于 WB,IP,FCM。

Anti-NRAS Antibody (8O77)

Anti-NRAS Antibody (8O77)

Rating icon 还可以
Anti-NRAS Antibody (8O77)
产品编号 TMAC-03537 别名 NS6, NRAS1, N-ras, neuroblastoma RAS viral (v-ras) oncogene homolog, NCMS, CMNS, ALPS4

Anti-NRAS Antibody (8O77) 是一种 Rabbit 抗体，靶向 NRAS。Anti-NRAS Antibody (8O77) 可用于 WB,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-NRAS Antibody (8O77) is a Rabbit antibody targeting NRAS. Anti-NRAS Antibody (8O77) can be used in WB,IP,FCM.
别名NS6, NRAS1, N-ras, neuroblastoma RAS viral (v-ras) oncogene homolog, NCMS, CMNS, ALPS4
Ig Type
IgG
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of Ras on different lysates using anti-Ras antibody at 1/1,000 dilution. Positive control: Lane 1: MCF-7, Lane 2: 293T, Lane 3: Mouse brain.
2. Flow cytometric analysis of Hela cells with Ras antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
IP
FCM
推荐剂量
WB: 1:1000-5000; FCM: 1:10-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Ras superfamily is a protein superfamily of small GTPases, which are all related, to a degree, to the Ras protein subfamily (the key human members of which are KRAS, NRAS, and HRAS). Receptor tyrosine kinases and G protein-coupled receptors activate Ras, which then stimulates the Raf-MEK-MAPK pathway. GTPase-activating proteins (GAP) normally facilitate the inactivation of Ras. However, research studies have shown that in 30% of human tumors, point mutations in Ras prevent the GAP-mediated inhibition of this pathway. The most common oncogenic Ras mutation found in tumors is Gly12 to Asp12 (G12D), which prevents Ras inactivation, possibly by increasing the overall rigidity of the protein. This antibody is predicted to react with H-Ras, N-Ras and K-Ras.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P01111
化学信息
分子量Theoretical: 18 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

NS-6NS 6NRAS-1NRAS 1ALPS-4ALPS 4

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4个月前
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