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Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
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货号 TMPK-00598
别名 IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
其他形式的 “Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated”:
Fc gamma RIIIA/CD16a (V176) Protein, Human, Recombinant (His & Avi), Biotinylated
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00598 别名 IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16
The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 568 | 现货 | |
| 10 μg | ¥ 928 | 现货 | |
| 20 μg | ¥ 1,530 | 3日内发货 | |
| 50 μg | ¥ 2,970 | 3日内发货 | |
| 100 μg | ¥ 5,180 | 现货 | |
| 200 μg | ¥ 9,390 | 5日内发货 | |
| 500 μg | ¥ 20,700 | 5日内发货 |
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纯度: > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
颜色: 白色
性状: Lyophilized powder
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产品介绍
生物活性
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| 产品描述 | The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| 生物活性 | 1. Immobilized Anti-Fc gamma RIIIA Antibody, hFc Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Fc gamma RIIIA (V176) , His Tag with the EC50 of 28.2ng/ml determined by ELISA (QC Test).
2. Rituximab captured on CM5 Chip via Protein A can bind Biotinylated Human Fc gamma RIIIA (V176) , His-Avi Tag with an affinity constant of 0.539 μM as determined in SPR assay. |
| 研究背景 | The Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-His-Avi |
| 蛋白编号 | AAH17865 |
| 蛋白构建 | Gly17-Gln208(V176) |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | IMD20, IGFR3, FcRIIIa, FcRIII, FcR-10, FcgRIIIA, FCGRIII, FCGR3A, FCGR3, FCG3, Fc γ RIIIA/CD16a (V176), Fc γ RIIIA, Fc gamma RIIIA, CD16A, CD16 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 24.7 kDa (predicted). Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| 存储 |
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