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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-EXOSC4 Polyclonal Antibody

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货号 TMAB-05744

Anti-EXOSC4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EXOSC4。Anti-EXOSC4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EXOSC4 Polyclonal Antibody

Anti-EXOSC4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05744

Anti-EXOSC4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 EXOSC4。Anti-EXOSC4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-EXOSC4 Polyclonal Antibody is a Rabbit antibody targeting EXOSC4. Anti-EXOSC4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus, nucleolus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3’ region. EXOSC4 (exosome component 4), also known as SKI6, RRP41 or p12A, is a 245 amino acid protein that localizes to both the nucleus and the cytoplasm and shares 96% sequence identity with its mouse counterpart. Functioning as a component of the exosome complex, EXOSC4 exhibits 3'-5' exonuclease activity and is required for the 3'-processing of 7S pre-RNA to mature 5.8S rRNA. The gene encoding EXOSC4 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EXOSC4
抗原种属
Human
基因名称
EXOSC4
基因ID
54512
蛋白名称
Exosome complex component RRP41
Uniprot ID
Q9NPD3
功能
EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.
化学信息
分子量Theoretical: 26 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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