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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FCGRT Polyclonal Antibody

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货号 TMAB-05947

Anti-FCGRT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FCGRT。Anti-FCGRT Polyclonal Antibody 可用于 WB,FCM。

Anti-FCGRT Polyclonal Antibody

Anti-FCGRT Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05947

Anti-FCGRT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FCGRT。Anti-FCGRT Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

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产品描述
Anti-FCGRT Polyclonal Antibody is a Rabbit antibody targeting FCGRT. Anti-FCGRT Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Sheep)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 3μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn å chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FCGRT/FcRn
抗原种属
Human
基因名称
FCGRT
基因ID
2217
蛋白名称
IgG receptor FcRn large subunit p51
Uniprot ID
P55899
功能
Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus.
化学信息
分子量Theoretical: 37 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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