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STAT1 Protein, Human, Recombinant

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货号 TMPJ-00961

别名 Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta

Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

STAT1 Protein, Human, Recombinant
其他形式的 “STAT1 Protein, Human, Recombinant”:
STAT1 Protein, Human, Recombinant (His & GST)TMPY-02240
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STAT1 Protein, Human, Recombinant

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货号 TMPJ-00961 别名 Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta

Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

规格价格库存数量
5 μg
¥ 492
现货
10 μg
¥ 820
6-8日内发货
20 μg
¥ 1,290
5日内发货
50 μg
¥ 2,480
5日内发货
100 μg
¥ 3,970
5日内发货
200 μg
¥ 6,760
5日内发货
500 μg
¥ 13,200
5日内发货
1 mg
¥ 18,900
5日内发货
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选择批次:
纯度: Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号P42224
氨基酸序列Met1-Val712
蛋白构建Met1-Val712
蛋白纯度
Greater than 68% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 0.02% Tween 80, 5% Sucrose, 4% Mannitol, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Transcription Factor ISGF-3 Components p91/p84, STAT1, Signal Transducer and Activator of Transcription 1-α/β, Signal Transducer and Activator of Transcription 1-α/Beta, Signal Transducer and Activator of Transcription 1-Alpha/Beta
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量85 KDa (reducing condition)
颜色White
物理性状Lyophilized powder
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

STAT-1STAT 1
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