规格

价格

库存

数量

5 μg

¥ 297

3日内发货

10 μg

¥ 487

3日内发货

20 μg

¥ 793

现货

50 μg

¥ 1,380

20日内发货

100 μg

¥ 2,170

20日内发货

200 μg

¥ 3,920

20日内发货

500 μg

¥ 8,660

20日内发货

1 mg

¥ 15,800

20日内发货

生物活性

产品描述	PARP14 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Has been shown to catalyze the mono-ADP-ribosylation of STAT1 at 'Glu-657' and 'Glu-705', thus decreasing STAT1 phosphorylation which negatively regulates pro-inflammatory cytokine production in macrophages in response to IFNG stimulation. However, the role of ADP-ribosylation in the prevention of STAT1 phosphorylation has been called into question and it has been suggested that the inhibition of phosphorylation may be the result of sumoylation of STAT1 'Lys-703'. Mono-ADP-ribosylates STAT6; enhancing STAT6-dependent transcription. In macrophages, positively regulates MRC1 expression in response to IL4 stimulation by promoting STAT6 phosphorylation. Mono-ADP-ribosylates PARP9.
种属	Human
表达系统	HEK293 Cells
标签	N-10xHis, C-Myc
蛋白编号	Q460N5
氨基酸序列	IPAHWSDMKQQNFCVVELLPSDPEYNTVASKFNQTCSHFRIEKIERIQNPDLWNSYQAKKKTMDAKNGQTMNEKQLFHGTDAGSVPHVNRNGFNRSYAGKNAVAYGKGTYFAVNANYSANDTYSRPDANGRKHVYYVRVLTGIYTHGNHSLIVPPSKNPQNPTDLYDTVTDNVHHPSLFVAFYDYQAYPEYLITFRK
蛋白构建	1605-1801 aa
蛋白纯度	> 90% as determined by SDS-PAGE.
缓冲液	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Protein mono-ADP-ribosyltransferase PARP14, Poly [ADP-ribose] polymerase 14 (PARP-14), PARP14, KIAA1268, BAL2, B aggressive lymphoma protein 2, ADP-ribosyltransferase diphtheria toxin-like 8 (ARTD8)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	27.6 kDa (predicted)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

PARP14 Protein, Human, Recombinant (His & Myc)

PARP14 Protein, Human, Recombinant (His & Myc)

产品介绍

引用文献

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