Anti-TRAF6 Polyclonal Antibody is a Rabbit antibody targeting TRAF6. Anti-TRAF6 Polyclonal Antibody can be used in WB.

IgG

Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep)

Sample:
Lane 1: Rat Liver tissue lysates
Lane 2: Rat Kidney tissue lysates
Primary: Anti-TRAF6 (TMAB-01884) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60 kDa
Observed band size: 60 kDa

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human TRAF6

Human

TRAF6

TNF receptor-associated factor 6

Associated Proteins,TRAF,TNF,TRAF,Associated Proteins,TLR Signaling,SARS Coronavirus,TNF,NFkB Pathway

E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation.