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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CPSF2 Polyclonal Antibody

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货号 TMAB-04619

Anti-CPSF2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPSF2。Anti-CPSF2 Polyclonal Antibody 可用于 WB。

Anti-CPSF2 Polyclonal Antibody

Anti-CPSF2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04619

Anti-CPSF2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CPSF2。Anti-CPSF2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CPSF2 Polyclonal Antibody is a Rabbit antibody targeting CPSF2. Anti-CPSF2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Cow,Horse,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nuclear.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CPSF contains four subunits and localizes to the nucleoplasm where it recognizes the AAUAAA signal in pre-mRNA and interacts with other proteins to facilitate RNA cleavage and poly(A) synthesis (1,4,5). The human CPSF2 gene maps to chromosome 14q32.12 and encodes the second largest subunit of cleavage and polyadenylation specificity factor. U1 snRNP-A protein (U1A) interacts with and affects the activity of CPSF by stabilizing the interaction of CPSF with the AAUAAA-containing RNAs to increase the efficiency of polyadenylation .
抗原信息
免疫原
KLH conjugated synthetic peptide: human CPSF2
抗原种属
Human
基因名称
CPSF2
基因ID
53981
蛋白名称
Cleavage and polyadenylation specificity factor subunit 2
Uniprot ID
Q9P2I0
功能
CPSF2 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF2/YSH1 subfamily. It is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3 prime-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. A poly(A) tail is added to eukaryotic mRNA precursors after tightly coupled cleavage and polyadenylation reactions at their 3-prime ends.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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