Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)

Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9.

规格	价格/CNY		数量
10 μg	￥ 550	5日内发货
50 μg	￥ 1,670	5日内发货
500 μg	￥ 13,700	5日内发货
1 mg	￥ 20,500	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 550

5日内发货

50 μg

￥ 1,670

5日内发货

500 μg

￥ 13,700

5日内发货

1 mg

￥ 20,500

5日内发货

生物活性	1. Loaded Anti-Human Nectin-4 mAb-mFc on AMQ Biosensor, can bind Cynomolgus Nectin-4-Fc with an affinity constant of 1.02 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Anti-Human Nectin-4 mAb-mFc at 2μg/ml (100 μl/well) can bind Cynomolgus Nectin-4-Fc. The ED50 of Cynomolgus Nectin-4-Fc is 4.93 ng/ml. (Regularly tested)
产品描述	Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-90 KDa and the accession number is L0N6D9.

种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	L0N6D9
别名	PRR4, Ig superfamily receptor LNIR, PVRL4, Poliovirus receptor-related protein 4, Nectin-4, LNIR
氨基酸序列	Gly32-Ser349
蛋白构建	Gly32-Ser349
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	80-90 KDa, reducing conditions

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20m PB, 150 mM NaCl, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Nectin-4 (PVRL4) is a type I transmembrane glycoprotein which belongs to the nectin family of Ig superfamily proteins. It contains two Ig-like C2-type domains and one Ig-like V-type domain. PVRL4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with nectin-1. It does not act as receptor for alpha-herpesvirus entry into cells. It is predominantly expressed in placenta, the embryo and breast carcinoma. But it is not detected in normal breast epithelium. The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder.

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Nectin-4 Protein, Cynomolgus, Recombinant (aa 32-349, hFc)

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