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Anti-Calponin 1+2+3 Polyclonal Antibody

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货号 TMAB-03581

Anti-Calponin 1+2+3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Calponin 1+2+3。Anti-Calponin 1+2+3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Calponin 1+2+3 Polyclonal Antibody

Anti-Calponin 1+2+3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-03581

Anti-Calponin 1+2+3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Calponin 1+2+3。Anti-Calponin 1+2+3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Calponin 1+2+3 Polyclonal Antibody is a Rabbit antibody targeting Calponin 1+2+3. Anti-Calponin 1+2+3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Heart and smooth muscle.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Calponin 1/2/3
抗原种属
Human
基因名称
CNN2
基因ID
1265
蛋白名称
Calponin-2
Uniprot ID
Q99439
功能
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
化学信息
分子量Theoretical: 34 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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