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Anti-ROBO4 Antibody (6G423)
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产品编号 TMAY-02167
别名 roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik
Anti-ROBO4 Antibody (6G423) 是一种 Rabbit 抗体，靶向 ROBO4。Anti-ROBO4 Antibody (6G423) 可用于 ELISA。
Anti-ROBO4 Antibody (6G423)
331 Anti-ROBO4 Antibody (6G423)
还可以产品编号 TMAY-02167 别名 roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik
Anti-ROBO4 Antibody (6G423) 是一种 Rabbit 抗体，靶向 ROBO4。Anti-ROBO4 Antibody (6G423) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,284 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-ROBO4 Antibody (6G423) is a Rabbit antibody targeting ROBO4. Anti-ROBO4 Antibody (6G423) can be used in ELISA. |
| 别名 | roundabout, axon guidance receptor, homolog 4 (Drosophila), Robo4, AI593217, 1200012D01Rik |
| Ig Type | Rabbit IgG |
| 克隆号 | 6G423 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ROBO4 (rh ROBO4; TMPY-02020; Q8WZ75-1; Met1-Glu469). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Roundabout homolog 4, also known as magic roundabout and ROBO4 is a member of the immunoglobulin superfamily and ROBO family. ROBO4 is specifically expressed in endothelial cells. It is expressed at sites of angiogenesis in different tumor types. ROBO4 contains two fibronectin type-III domains and two Ig-like C2-type (immunoglobulin-like) domains. ROBO4 is the fourth identified member of the roundabout receptor family. It is the only Robo family member expressed in primary endothelial cells and that application of Slit inhibits their migration. ROBO4 is predominantly expressed in embryonic or tumor vascular endothelium and is considered important for vascular development and as a candidate tumor endothelial marker. ROBO4 is a bona fide member of the Robo family and may provide a repulsive cue to migrating endothelial cells during vascular development. ROBO4 is a receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins. Activating ROBO4 may have broad therapeutic application in diseases characterized by excessive angiogenesis and/or vascular leak. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human ROBO4 protein (TMPY-02020) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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