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Anti-EMMPRIN/CD147 Antibody (8Q238)
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产品编号 TMAY-00419
别名 basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody (8Q238) 是一种 Mouse 抗体，靶向 EMMPRIN/CD147。Anti-EMMPRIN/CD147 Antibody (8Q238) 可用于 ELISA,ELISA(Cap),IHC-P。
Anti-EMMPRIN/CD147 Antibody (8Q238)
Anti-EMMPRIN/CD147 Antibody (8Q238)
还可以产品编号 TMAY-00419 别名 basigin (Ok blood group)
Anti-EMMPRIN/CD147 Antibody (8Q238) 是一种 Mouse 抗体，靶向 EMMPRIN/CD147。Anti-EMMPRIN/CD147 Antibody (8Q238) 可用于 ELISA,ELISA(Cap),IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 590 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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抗原信息
| 产品描述 | Anti-EMMPRIN/CD147 Antibody (8Q238) is a Mouse antibody targeting EMMPRIN/CD147. Anti-EMMPRIN/CD147 Antibody (8Q238) can be used in ELISA,ELISA(Cap),IHC-P. |
| 别名 | basigin (Ok blood group) |
| Ig Type | Mouse IgG2a |
| 克隆号 | 8Q238 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CD147 in human stomach with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell. 2. Immunochemical staining of human CD147 in human gastric cancer with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). The image showing membrane staining of epithelium cell. 3. Immunochemical staining of human CD147 in human esophagus with mouse monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). The image showing membrane staining of squamous epithelium cell. |
| 应用 | |
| 推荐剂量 | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200; ELISA(Cap): 1:250-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD147. (rh CD147; NP_940991.1Met 1-His 205). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CD147 protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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