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Anti-Utrophin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Utrophin。Anti-Utrophin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
Anti-Utrophin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Utrophin。Anti-Utrophin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-Utrophin Polyclonal Antibody 2 is a Rabbit antibody targeting Utrophin. Anti-Utrophin Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Chicken,Dog,Cow,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction > synapse > postsynaptic cell membrane. Cytoplasm > cytoskeleton. Neuromuscular junction. |
| 组织特异性 | Muscle. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology. |
| 免疫原 | KLH conjugated synthetic peptide: human Utrophin |
| 抗原种属 | Human |
| 基因名称 | UTRN |
| 基因ID | |
| 蛋白名称 | Utrophin |
| Uniprot ID | |
| 功能 | May play a role in anchoring the cytoskeleton to the plasma membrane. |
| 分子量 | Theoretical: 394 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |