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Anti-Utrophin Polyclonal Antibody 2

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货号 TMAB-14034

Anti-Utrophin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Utrophin。Anti-Utrophin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Utrophin Polyclonal Antibody 2

Anti-Utrophin Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-14034

Anti-Utrophin Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Utrophin。Anti-Utrophin Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-Utrophin Polyclonal Antibody 2 is a Rabbit antibody targeting Utrophin. Anti-Utrophin Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Chicken,Dog,Cow,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction > synapse > postsynaptic cell membrane. Cytoplasm > cytoskeleton. Neuromuscular junction.
组织特异性Muscle.
构建方式Hybridoma Polyclonal Antibody
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Dystrophin and utrophin are related structural, Actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin is the protein product of the Duchenne/Becker muscular dystrophy gene. Dystrophin expression is found in muscle and brain tissues, where it is localized to the inner surface of the plasma membrane. It has been speculated that alternative splicing of the carboxy terminus allows dystrophin to interact with a variety of proteins. Research has shown that the loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and that the lack of dystrophin results in the loss of linkage between the cytoskeleton and the extracellular matrix. Evidence suggests that the upregulation of utrophin can reduce the dystrophic pathology.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Utrophin
抗原种属
Human
基因名称
UTRN
基因ID
蛋白名称
Utrophin
Uniprot ID
功能
May play a role in anchoring the cytoskeleton to the plasma membrane.
化学信息
分子量Theoretical: 394 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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