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TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

产品编号 TMPJ-00333
别名: Transforming growth factor-β receptor type II, TbetaR-II, TGF-β type II receptor, TβR-II, TGFR-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II, TGF-beta type II receptor, TGF-β receptor type II, Tgfbr2, TGF-beta receptor type-2, TGF-β receptor type-2

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.

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TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
规格 价格/CNY 货期 数量
10 μg ¥ 890 5日内发货
50 μg ¥ 2,690 5日内发货
500 μg ¥ 13,500 5日内发货
1 mg ¥ 20,200 5日内发货
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产品目录号及名称: TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) (TMPJ-00333)
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产品描述 TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
种属 Mouse
表达系统 HEK293 Cells
标签 C-hFc
蛋白编号 Q62312
别名 Transforming growth factor-β receptor type II, TbetaR-II, TGF-β type II receptor, TβR-II, TGFR-2, TGF-beta receptor type II, Transforming growth factor-beta receptor type II, TGF-beta type II receptor, TGF-β receptor type II, Tgfbr2, TGF-beta receptor type-2, TGF-β receptor type-2
氨基酸序列 Ile24-Asp184
蛋白构建 Ile24-Asp184
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 60-75 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Transforming growth factor-β (TGF-β) is an essential regulator in the processes of development, cell proliferation, and extracellular matrix deposition. TGF-β regulates cellular processes by binding to three high-affinity cell surface receptors: TGF-β receptor type I (TGF-β-RI), TGF-β receptor type II (TGF-β-RII), and TGF-ββ receptor type III (TGF-β-RIII). TGF-β RII is consists of a C-terminal protein kinase domain and an N-terminal ectodomain and belongs to transforming growth factor-beta (TGF-β) receptor subfamily. TGF-β RII has a protein kinase domain which can form a heterodimeric complex with another receptor protein and bind TGF-beta. This receptor/ligand complex phosphorylates protein will enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation.

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Keywords

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Transforming growth factor-β receptor type II TGF-b type II receptor TbetaR-II TGF-b receptor type II TGF-β type II receptor Transforming growth factor-b receptor type II TβR-II TGFR-2 TGF-beta receptor type II TGFR2 Transforming growth factor-beta receptor type II TGF-beta type II receptor TGF-β receptor type II Tgfbr2 TGFR 2 TGF-b receptor type-2 TGF-beta receptor type-2 TGF-β receptor type-2 recombinant recombinant-proteins proteins protein

 

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