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别名 RIG, REIC, dickkopf WNT signaling pathway inhibitor 3
Anti-DKK3 Antibody (2C7) 是一种 Mouse 抗体,靶向 DKK3。Anti-DKK3 Antibody (2C7) 可用于 ELISA。
Anti-DKK3 Antibody (2C7) 是一种 Mouse 抗体,靶向 DKK3。Anti-DKK3 Antibody (2C7) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,694 | 5日内发货 |
| 产品描述 | Anti-DKK3 Antibody (2C7) is a Mouse antibody targeting DKK3. Anti-DKK3 Antibody (2C7) can be used in ELISA. |
| 别名 | RIG, REIC, dickkopf WNT signaling pathway inhibitor 3 |
| Ig Type | Mouse IgG1 |
| 克隆号 | 2C7 |
| 交叉反应 | Human |
| 特异性 | Human DKK-3 |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Dkk3 (rhDkk3; Met1-Ile350AAF02676.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human Dkk3 protein |
| 抗原种属 | Human |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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