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顶部生物活性储存和溶解信息计算器

Anti-HSPA5 Antibody (9M857)

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产品编号 TMAC-01725

别名 Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein

Anti-HSPA5 Antibody (9M857) 是一种 Mouse 抗体，靶向 HSPA5。Anti-HSPA5 Antibody (9M857) 可用于 ICC,IHC,WB。

Anti-HSPA5 Antibody (9M857)

Anti-HSPA5 Antibody (9M857)

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产品编号 TMAC-01725 别名 Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein

Anti-HSPA5 Antibody (9M857) 是一种 Mouse 抗体，靶向 HSPA5。Anti-HSPA5 Antibody (9M857) 可用于 ICC,IHC,WB。

规格价格库存数量
50 μL
¥ 1,985
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-HSPA5 Antibody (9M857) is a Mouse antibody targeting HSPA5. Anti-HSPA5 Antibody (9M857) can be used in ICC,IHC,WB.
别名Immunoglobulin heavy chain-binding protein, HSPA 5, HSP70 family protein 5, Heat shock protein family A member 5, Heat shock protein 70 family protein 5, GRP-78, GRP78, Endoplasmic reticulum chaperone BiP, EC 3.6.4.10, BiP, Binding-immunoglobulin protein, 78 kDa glucose-regulated protein
克隆号
9M857
交叉反应
Human
验证活性
1. Western blot analysis on human spermatozoa lysates using anti- GRP78 mouse mAb.
2. ICC staining GRP78 in Hela cells (red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivity
应用ICCIHCWB
推荐剂量
WB: 1:5000-10000; ICC: 1:200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a protein that in humans is encoded by the HSPA5 gene. BiP is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER) that binds newly synthesized proteins as they are translocated into the ER, and maintains them in a state competent for subsequent folding and oligomerization. BiP is also an essential component of the translocation machinery, as well as playing a role in retrograde transport across the ER membrane of aberrant proteins destined for degradation by the proteasome. Like many stress and heat shock proteins, BiP/GRP78 has potent immunological activity when released from the internal environment of the cell into the extracelluar space.specifically, it feeds inflammatory and pro-resolutory signals into immune networks, thus helping to resolve inflammation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Peptide
Uniprot ID
P11021
化学信息
分子量Theoretical: 78 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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