购物车
- 全部删除
您的购物车当前为空
Anti-LAMP1 Antibody-FITC (4R795)
还可以产品编号 TMAY-01761F
Anti-LAMP1 Antibody-FITC (4R795) 是一种 FITC-conjugated Rabbit 抗体，靶向 LAMP1。Anti-LAMP1 Antibody-FITC (4R795) 可用于 FCM。
Anti-LAMP1 Antibody-FITC (4R795)
Anti-LAMP1 Antibody-FITC (4R795)
还可以产品编号 TMAY-01761F
Anti-LAMP1 Antibody-FITC (4R795) 是一种 FITC-conjugated Rabbit 抗体，靶向 LAMP1。Anti-LAMP1 Antibody-FITC (4R795) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LAMP1 Antibody-FITC (4R795) is a FITC-conjugated Rabbit antibody targeting LAMP1. Anti-LAMP1 Antibody-FITC (4R795) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4R795 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human LAMP1 (CD107a) expression in Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Mouse anti-LAMP1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human LAMP-1 / CD107a (rh LAMP-1 / CD107a; TMPY-01253; NP_005552.3; Met1-Met382) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Lysosome-associated membrane glycoprotein 1, also known as CD107 antigen-like family member A, CD107a, and LAMP1, is a single-pass type I membrane protein that belongs to the LAMP family. CD107a is expressed largely in the endosome-lysosome membranes of cells but is also found on the plasma membrane (1-2% of total LAMP1). LAMP1 has been implicated in a variety of cellular functions, including cancer metastasis. It has been proposed LAMP1 serves as a therapeutic agent for some cancers, as well as a marker for lysosomal storage disorders and different cell types such as cytotoxic T cells. LAMP2, also known as CD107b, may also play a role in tumor cell metastasis and functions in the protection, maintenance, and adhesion of the lysosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation. LAMP-1 is a glycoprotein highly expressed in lysosomal membranes. The present study was initiated to test LAMP-1 mRNA and protein levels in post mortem frontal cortex (area 8) of Alzheimer's disease (AD) stages I-IIA/B and stages V-VIC of Braak and Braak, compared with age-matched controls. LAMP-1 occurred in microglia and multinucleated giant cells in one AD case in which amyloid burden was cleared following beta A-peptide immunization. Also, LAMP-1 has been suggested to be a cell surface receptor for a specific amelogenin isoform, leucine-rich amelogenin peptide, or LRAP. LAMP-1 can serve as a cell surface binding site for amelogenin on dental follicle cells and cementoblasts. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human LAMP-1 / CD107a protein (TMPY-01253) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-LAMP1 Antibody-FITC (4R795) | purchase Anti-LAMP1 Antibody-FITC (4R795) | Anti-LAMP1 Antibody-FITC (4R795) cost | order Anti-LAMP1 Antibody-FITC (4R795)
嗨！有任何问题？点我咨询
评论内容